Cyp6a2
WebGene target information for Cyp6a2 - Cytochrome P450 6a2 (fruit fly). Find diseases associated with this biological target and compounds tested against it in bioassay … WebFeb 15, 2024 · Compared to other alleles, Cyp6a2 Canton-S-1 lacks a 15bp fragment in the 5' core promoter region. This region forms part of a canonical binding site for the Nrf2/Maf heterodimer. The Cyp6a2 Canton-S-1 allele also has a 513-bp insertion of a 17.6 element in the 3' UTR. (Wan et al., 2014)
Cyp6a2
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WebThe mRNA transcriptional levels of CYP6A2 increased signi fi cantly in the resistant strain compared with the susceptible strain, with ap- proximately 5.25- and 4.19-fold over-expression for ... WebRESULTS: Molecular analysis identified five Cyp6a2 alleles (Cyp6a2 Canton-S-1, Cyp6a2 Canton-S-2, Cyp6a2 91-C, Cyp6a2 91-R and Cyp6a2 Wisconsin-WD) from four …
WebJan 1, 2016 · Our research indicated that CYP6A2 was the only up-regulated P450 gene among the differentially expressed genes (DEGs) in the spirotetramat-resistant strain via … WebInformation about Cytochrome P450 6A2 (CYP6A2) Genotyping . Search our extensive database of medical/laboratory tests and review in-depth information about each test. Cytochrome P450 6A2 (CYP6A2) Genotyping - Medical Laboratory Tests - Seach, Database, Information
The psiCHECK-2 dual fluorescent reporter system (Promega, Madison, WI, USA) was used to determine any interaction of miR-310s with putative target binding sites in Cyp6g1 and Cyp6g2. The psiCHECK-2 system incorporates Renilla luciferase as a reporter gene and firefly luciferase as a control to normalize for … See more The DDT-susceptible Canton-S, the low-level DDT-resistant 91-C, and the highly DDT-resistant 91-R strains of Drosophila have been … See more First-strand cDNA synthesis was performed using the miScript II RT kit (Qiagen). Each synthesized cDNA sample was then used as a template for RT-qPCR reactions using the miScript SYBR Green PCR Kit (Qiagen) … See more A set of mirVana mimics were synthesized for miR-310, miR-311, miR-312, and miR-313 by Invitrogen (Ambion, Life Technologies) at a … See more One-day-old female 91-R (90 flies per each injection) were injected separately with miR-310s mimics, NCsiRNA, and DEPC-water using … See more WebDegenerate primers corresponding to conserved amino acid sequences in three insect P450s, Musca domestica (CYP6A1), Drosophila melanogaster (CYP6A2) and Papilio polyxenes (CYP6B1), were used to clone xanthotoxin-induced P450 transcripts from P. glaucus larvae by a reverse transcription-polymerase chain reaction (RT-PCR) strategy.
WebJul 25, 2024 · 1. Introduction. Accounting for 85-90% of primary liver malignancy, hepatocellular carcinoma (HCC) is the fifth most common tumor worldwide and the second most common cause of cancer-related death [1–4].Over the last 20 years, the incidence of HCC has been rising in the United States and China [1, 2].Given the complexity of the …
WebFeb 28, 2024 · Nanostructures. DN and GN powders were purchased from Skyspring Nanomaterials Inc. (Houston, TX, USA). Both nanoparticles were produced by the explosive method and synthesized to 3–4 nm. list of shows on filmriseWebBarbital (or barbitone), marketed under the brand names Veronal for the pure acid and Medinal for the sodium salt, was the first commercially available barbiturate.It was used as a sleeping aid from 1903 until the mid-1950s.The chemical names for barbital are diethylmalonyl urea or diethylbarbituric acid; hence, the sodium salt (known as medinal, … list of shows on netflixWebAlthough Cyp6a2 has been observed to be overexpressed in many 4,4′‐dichlorodiphenyltrichloroethane (DDT)‐resistant strains of Drosophila melanogaster, how Cyp6a2 is regulated and whether its overproduction confers DDT resistance remain elusive. immature towheeWebApr 14, 2024 · Objective: To investigate the dominant metabolic enzymes of six effective components (astragaloside IV, glycyrrhizic acid, calycosin-glucuronide, formononetin, ononin, calycosin-7-O-β-D- glucoside) of Huangqi Liuyi decoction extract (HQD).Methods: Mouse liver microsomes were prepared. The effects of specific inhibitors of CYP450 … list of shows on showtimeWebFeb 23, 2024 · Cyp6a2 provided by FlyBase Official Full Name Cytochrome P450 6a2 provided by FlyBase Primary source FLYBASE:FBgn0000473 Locus tag Dmel_CG9438 … list of shows on food networkWebSep 4, 2013 · Although Cyp6a2 has been observed to be overexpressed in many 4,4′‐dichlorodiphenyltrichloroethane (DDT)‐resistant strains of Drosophila melanogaster, … list of shows on peacock premiumWebJun 30, 2014 · TL;DR: The results suggest that the Nrf2/Maf binding-site-containing functional Cyp6a2 allele is associated with DDT resistance in the D. melanogaster strains under study. Abstract: BACKGROUND Increased insecticide detoxification mediated by cytochrome P450s is a common mechanism of insecticide resistance. Although Cyp6a2 … list of shows on hulu 2022