Web19 mrt. 2024 · 43observed densities have been shown to consist of long chains of IFT particles, which themselves 44consist of two protein complexes (IFT-A and IFT-B) as well as motors and cargo (Cole et al., 1998; 45Pigino et al., 2009;Taschner and Lorentzen, 2016;Jordan et al., 2024). Since the initial discov- Web11 apr. 2024 · Using NASA's Imaging X-ray Polarimetry Explorer (IXPE) spacecraft, Niccolò Bucciantini at the INAF Arcetri Observatory in Italy and his colleagues were able to trace the Crab Nebula's magnetic ...
Assembly and stability of IFT-B complex and its function in …
WebThe IFT-B complex mediates ciliary anterograde protein trafficking and membrane protein export together with the BBSome. Bardet-Biedl syndrome (BBS) is caused by mutations … Web28 aug. 2024 · IFT-B subunit are essential for ciliogenesis [18]. IFT74, together with its short protein variant, IFT72, forms a heterotetramer with IFT81, composing the backbone of the IFT-B core complex. The interaction between IFT74 and IFT81 proteins forms a module that is essential for the binding of tubulin, shiraz location
Biochemically validated structural model of the 15‐subunit ...
WebNational Center for Biotechnology Information Web9 aug. 2024 · Intraflagellar transport (IFT) trains are molecular machines that traffic proteins between cilia and the cell body. With a molecular weight over 80 MDa, each IFT train is a dynamic polymer of two large complexes (IFT-A and -B) and motor proteins, posing a formidable challenge to mechanistic understanding. WebTheir biogenesis and function are mediated by the intraflagellar transport (IFT) system. Pathogenic variants in IFT52, a central component of the IFT-B complex is associated … shiraz market longwood menu