WebSep 26, 2024 · Furthermore, patients with high phospho-Drp1 Ser616 are associated with high risk on developing tumor relapse, poor 5-year disease-free survival (DFS) and 5-year … WebMay 27, 2024 · Antibodies against Phospho-RIP3 (Thr231/Ser232) and Phospho-Drp1 (Ser616) were purchased from Cell Signaling Technology (Danvers, MA, USA). The Aggresome Detection Kit was acquired from Abcam (Cambridge, MA, USA). MitoTracker Deep Red, the ROS 2′,7′-dichlorodihydrofluorescein diacetate (DCFH-DA) kit, …
Prognostic impact of Dynamin related protein 1 (Drp1) in epithelial ...
WebPhospho (Ser616) View Product On Supplier's Website Request a Quote from Cell Signaling Technology Supplier provided information Immunogen Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser616 of human DRP1. WebAug 5, 2024 · Reduced Drp1 S616 phosphorylation is detected in fibroblasts derived from 4 PD patients harboring PINK1 mutations and in 4 out of 7 sporadic PD cases. Taken together, we have identified Drp1 as a substrate of PINK1 and a novel mechanism how PINK1 regulates mitochondrial fission independent of parkin and autophagy. notre dame football schedule 2008
HMGB1 promotes ERK-mediated mitochondrial Drp1 …
WebThe glomerular expression of Drp1, phospho-Drp1 (Ser616) and Fis1, urinary protein measurements, and podocyte mitochondrial density under electron microscopy were … WebApr 19, 2024 · In the hypertrophied muscle, the level of activated dynamin-related protein 1 (Drp1), phosphorylated at Ser616, significantly increased by 25.8% ( p = 0.014). Moreover, the protein expression level of mitochondrial fission factor significantly decreased by 36.5% in the hypertrophy group compared with that of the control group ( p = 0.017). WebPhospho-DRP1 (Ser616) Antibody detects endogenous levels of DRP1 only when phosphorylated at Ser616. Species Reactivity: Human. Species … notre dame football schedule 2015